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Infectious Disease Talks

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Talks related to infectious diseases
URL: http://talks.cam.ac.uk/show/index/29729
Updated: 54 min 27 sec ago

Wed 21 Feb 12:00: New Strategies for how modification enzymes distinguish tRNAs (or not)

Mon, 12/02/2024 - 09:46
New Strategies for how modification enzymes distinguish tRNAs (or not)

Abstract not available

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Tue 13 Feb 12:00: Visualizing virus infection in situ by cryoET

Mon, 12/02/2024 - 09:45
Visualizing virus infection in situ by cryoET

Abstract not available

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Wed 14 Feb 14:00: Understanding Virus Evolution and Outbreaks through Phylodynamics: From Theory to Practice

Wed, 07/02/2024 - 10:06
Understanding Virus Evolution and Outbreaks through Phylodynamics: From Theory to Practice

Abstract: The recent increase in viral-driven outbreaks, epidemics, and pandemics highlights the necessity to understand virus evolution and disease dynamics within changing ecological contexts. Multidisciplinary research approaches informing phylodynamic and genomic epidemiology have proven essential in unravelling viral evolutionary trajectories and epidemiological dynamics across different scales. This talk aims to share insights from the field and my own research, emphasizing on how exploring convergent evolution can be a valuable tool for tracing common evolutionary pathways in RNA viruses relevant for global health. Additionally, I will showcase the potential applications of these approaches in enhancing targeted virus surveillance programs, using my work in Mexico as an illustrative example.

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Fri 21 Jun 13:00: Genetics and Environment Induce Loss of FoxP3+ Regulatory T cell Function in Autoimmunity

Tue, 06/02/2024 - 16:30
Genetics and Environment Induce Loss of FoxP3+ Regulatory T cell Function in Autoimmunity

This Cambridge Immunology and Medicine Seminar will take place on Friday 21 June 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Speaker: David A. Hafler, M.D. Edgerly Professor of Neurology and Immunobiology, Chairman, Department of Neurology, Yale School of Medicine

Host: Professor Menna R. Clatworthy, NIHR Research Professor and Professor of Translational Immunology, University of Cambridge

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

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Fri 24 May 13:00: Title - TBC

Tue, 06/02/2024 - 16:25
Title - TBC

This Cambridge Immunology and Medicine Seminar will take place on Friday 24 May 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Speaker: Dr Karen Mackenzie, Fellow and Honorary Consultant in Clinical Genetics, Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh

Host: James Nathan, Wellcome Senior Clinical Fellow, Professor of Respiratory Medicine, University of Cambridge

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

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Fri 24 May 13:00: Title - TBC

Tue, 06/02/2024 - 16:12
Title - TBC

his Cambridge Immunology and Medicine Seminar will take place on Friday 24 May 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Speaker: Dr Karen Mackenzie, Fellow and Honorary Consultant in Clinical Genetics, Centre for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh

Host: James Nathan, Wellcome Senior Clinical Fellow, Professor of Respiratory Medicine, University of Cambridge

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

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Fri 10 May 13:00: Title - TBC

Tue, 06/02/2024 - 16:00
Title - TBC

This Cambridge Immunology and Medicine Seminar will take place on Friday 10 May 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Speaker: Professor Simon Davis, MRC Translational Immune Discovery Unit, Radcliffe Department of Medicine, Oxford

Host: Clare Bryant, Professor of Innate Immunity, Department of Medicine, University of Cambridge.

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

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Wed 07 Feb 14:00: Generating Medium-Term Projections of Covid-19 for Wales.

Mon, 05/02/2024 - 14:24
Generating Medium-Term Projections of Covid-19 for Wales.

One of the key tools used by the Welsh Government during its devolved pandemic decision-making was a stochastic, age-structured, local authority level, epidemiological model, designed to capture the key dynamics, and project the potential future spread and hospital impact under a range of formal assumptions. Some of these models are complex and often take several seconds or minutes to generate a single simulation on several indicators of interest, e.g. prevalence, deaths, hospital admissions, and intensive care burden. The typical approach to fitting the models to observed data consists of optimising model parameters to fit a weighted sum of the mean squared errors (MSE) between the model output and multiple time series data. In this work, we combined MSE and maximum absolute distance between projections and data using augmented Tchebyshev scalarisation as a measure of the error. Furthermore, to combat the computational expense of optimising up to 50 parameters of the model, we used a multi-objective Bayesian optimisation approach to simultaneously minimise the errors between six time-series projections and data. This approach yielded a good approximation of the sets of parameters that generated (near-)optimal trade-off fits between different targets, and was easily generalisable in post-processing if different weights were required for each data stream. The resultant trade-off front allowed us to interactively generate appropriate visual aids, and, most importantly, “Medium-Term Projections” (MTPs) for Wales, deemed plausible by experts. Our generated MTPs have been prepared in collaboration with the Scientific Pandemic Influenza Group on Modelling (SPI-M) and the UK Health Security Agency (UKHSA), and included in their weekly published reports. They were updated weekly, and delivered to stakeholders in Welsh Government, Public Health Wales, the NHS Wales Hospital Trusts, the Ambulance Trust, and directly impacted planning, assessment and decision-making.

  • Speaker: Daniel Archambault (Newcastle University) & Alma Rahat (Swansea University)
  • Wednesday 07 February 2024, 14:00-15:00
  • Venue: Zoom.
  • Series: Worms and Bugs; organiser: Dr Ciara Dangerfield.

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Wed 07 Feb 14:00: What is still so fascinating about the trypanosome coat?

Wed, 31/01/2024 - 17:40
What is still so fascinating about the trypanosome coat?

The cell surface coat of African trypanosomes has been studied for a long time. So you could assume that all the essentials are known. However, this is not the case. In my talk, I focus on the fabric from which this coat is woven (the VGSs) and their incredible dynamics. We’ve known for 20 years that the VSG coat can be recycled quickly, and we have a good idea of why. However, how the underlying biological processes can take place at such high speeds is only gradually coming to light. We’re trying to put the puzzle together step by step. In doing so, we sometimes come across surprising insights that can shed new light on basic cell biology. That’s what I’m going to tell you about. In addition, I would like to make my talk a plea for continuing research into parasitic protozoa, whose extreme adaptations can expand our reductionist perspective on cell biology.

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Wed 28 Feb 13:00: Bradford Hill Seminar - Social justice and health equity

Tue, 30/01/2024 - 16:57
Bradford Hill Seminar - Social justice and health equity

Register to attend Please note this will be online webinar. Professor Sir Michael Marmot will present online via Teams.

Register on Teams to attend seminar online at https://events.teams.microsoft.com/event/e8489407-d5e4-4d3e-a91e-d95a97ed97e8@49a50445-bdfa-4b79-ade3-547b4f3986e9

Abstract Taking action to reduce health inequalities is a matter of social justice. In developing strategies for tackling health inequalities we need to confront the social gradient in health not just the difference between the worst off and everybody else. There is clear evidence when we look across countries that national policies make a difference and that much can be done in cities, towns and local areas. But policies and interventions must not be confined to the health care system; they need to address the conditions in which people are born, grow, live, work and age. The evidence shows that economic circumstances are important but are not the only drivers of health inequalities. Tackling the health gap will take action, based on sound evidence, across the whole of society.

About Professor Sir Michael Marmot Sir Michael Marmot MBBS , MPH, PhD, FRCP , FFPHM, FMedSci, FBA has been Professor of Epidemiology at University College London since 1985. He is the author of The Health Gap: the challenge of an unequal world (Bloomsbury: 2015), and Status Syndrome: how your place on the social gradient directly affects your health (Bloomsbury: 2004). Professor Marmot is the Advisor to the WHO Director-General, on social determinants of health, in the new WHO Division of Healthier Populations; Distinguished Visiting Professor at Chinese University of Hong Kong (2019-), and co-Director of the of the CUHK Institute of Health Equity. He is the recipient of the WHO Global Hero Award; the Harvard Lown Professorship (2014-2017); the Prince Mahidol Award for Public Health (2015), and 19 honorary doctorates.

Marmot has led research groups on health inequalities for nearly 50 years. He chaired the Commission on Equity and Health Inequalities in the Americas, set up in 2015 by the World Health Organization’s Pan-American Health Organization (PAHO/ WHO ) and chaired the Commission on Social Determinants of Health (CSDH), which was set up by the World Health Organization in 2005, and produced the report entitled: ‘Closing the Gap in a Generation’ in August 2008. At the request of the British Government, he conducted the Strategic Review of Health Inequalities in England post 2010, which published its report ‘Fair Society, Healthy Lives’ in February 2010. This was followed by the European Review of Social Determinants of Health and the Health Divide, for WHO EURO in 2014; Health Equity in England: Marmot Review 10 Years On, in 2020; Build Back Fairer: the COVID -19 Marmot Review in 2021; and the Report of the Commission on Social Determinants of Health in the Eastern Mediterranean Region, for WHO EMRO , also in 2021.

Professor Marmot also chaired the Expert Panel for the WCRF /AICR 2007 Second Expert Report on Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective; the Breast Screening Review for the NHS National Cancer Action Team, and was a member of The Lancet-University of Oslo Commission on Global Governance for Health. Early in his career, he set up and led a number of longitudinal cohort studies on the social gradient in health in the UCL Department of Epidemiology & Public Health (where he was head of department for 25 years): the Whitehall II Studies of British Civil Servants, investigating explanations for the striking inverse social gradient in morbidity and mortality; the English Longitudinal Study of Ageing (ELSA), and several international research efforts on the social determinants of health. He served as President of the British Medical Association (BMA) in 2010-2011, and as President of the World Medical Association in 2015. He is President of the British Lung Foundation. He is an Honorary Fellow of the American College of Epidemiology; a Fellow of the Academy of Medical Sciences; an Honorary Fellow of the British Academy, and an Honorary Fellow of the Faculty of Public Health of the Royal College of Physicians. He was a member of the Royal Commission on Environmental Pollution for six years and in 2000 he was knighted by Her Majesty The Queen, for services to epidemiology and the understanding of health inequalities. Professor Marmot is a Member of the National Academy of Medicine.

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Fri 22 Mar 13:00: Title - TBC

Tue, 30/01/2024 - 10:10
Title - TBC

This Cambridge Immunology and Medicine Seminar will take place on Friday 22 March 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC):

Speaker: Dr Sara Ghorashian, Honorary Senior Clinical Lecturer, University College London and Consultant Paediatric Haematologist, Great Ormond Street Hospital

Host: Professor Rahul Roychoudhuri, Professor of Cancer Immunology, University of Cambridge.

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom Refreshments will be available following the Seminar.

This talk is part of the Immunology and Medicine Seminars series.

If you have a question about this talk, please contact Ruth Paton

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Fri 08 Mar 13:00: Title - TBC

Tue, 30/01/2024 - 09:48
Title - TBC

The next Cambridge Immunology and Medicine Seminar will take place on Friday 8th March 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Speaker: Professor Luca Gattinoni, Division of Functional Immune Cell Modulation, Leibniz Institute for Immunotherapy

Host: Professor Rahul Roychoudhuri, Professor of Cancer Immunology (Department of Pathology) and Director (non-clinical) of the CRUK Cambridge Centre Training Programme, at the University of Cambridge.

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

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Fri 16 Feb 13:00: Mechanisms controlling gene expression in hypoxia and inflammation

Tue, 30/01/2024 - 09:10
Mechanisms controlling gene expression in hypoxia and inflammation

Professor Sonia Rocha, Executive Dean of the Institute of Systems Molecular and Integrative Biology, University of Liverpool.

The next Cambridge Immunology and Medicine Seminar will take place on Friday 16th February 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Host: Professor James Nathan, Wellcome Senior Clinical Fellow, Professor of Respiratory Medicine, University of Cambridge.

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

If you have a question about this talk, please contact Ruth Paton.

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Fri 08 Mar 15:00: Title to be confirmed

Fri, 26/01/2024 - 12:02
Title to be confirmed

Abstract not available

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Fri 01 Mar 15:00: Title to be confirmed

Fri, 26/01/2024 - 12:02
Title to be confirmed

Abstract not available

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Fri 23 Feb 15:00: Introducing the Tchasovnikarova Lab

Fri, 26/01/2024 - 12:01
Introducing the Tchasovnikarova Lab

Abstract not available

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Fri 16 Feb 15:00: Title to be confirmed

Fri, 26/01/2024 - 12:00
Title to be confirmed

Abstract not available

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Fri 02 Feb 15:00: Disorder at different length scales from a chromatin perspective

Fri, 26/01/2024 - 11:59
Disorder at different length scales from a chromatin perspective

Abstract not available

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Tue 06 Feb 12:00: Airway Biology at the Nanoscale

Tue, 23/01/2024 - 15:41
Airway Biology at the Nanoscale

A significant frontier in Spatial Biology is the construction of an integrated view of tissue function within its native environment at the cellular and molecular levels. In this seminar, we will explore how the combination of nanometre-scale imaging modalities, AI segmentation algorithms, and protein-protein interaction mapping in human tissue models is providing a novel perspective on airway biology and creating opportunities for translational medicine research. The primary focus will be on the respiratory epithelium, a critical tissue that safeguards our lungs by serving as the first line of defence against bacteria, viruses, and particulate matter. We will provide examples illustrating how this multimodal spatial biology approach is revealing the molecular mechanisms underlying airway protection from pathogens.

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Fri 19 Jan 13:00: ILC2 regulation of tissue-localised immunity... and beyond

Fri, 19/01/2024 - 00:34
ILC2 regulation of tissue-localised immunity... and beyond

Andrew McKenzie FRS F MedSci is a molecular biologist and group leader in the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).

The next Cambridge Immunology and Medicine Seminar will take place on Friday 19th January 2024, starting at 1:00 pm, in the Ground Floor Lecture Theatre, Jeffrey Cheah Biomedical Centre (JCBC)

Host: Professor Menna Clatworthy, Professor of Translational Immunology, University of Cambridge.

For anyone who can’t attend in person, please join the Cambridge Immunology and Medicine Seminar on Zoom:

Please note the Zoom link has changed from previous communications.

Join Zoom Meeting: https://cam-ac-uk.zoom.us/j/89741634903?pwd=dzcxbU45NjAwQXo1dmlNMjR3V0lUUT09

Meeting ID: 897 4163 4903 Passcode: 539740

Refreshments will be available following the Seminar.

If you have a question about this talk, please contact Ruth Paton.

Add to your calendar or Include in your list

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