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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

Professor Andres Floto

Professor Andres Floto

The response of Macrophages and Dendritic cells to bacterial and mycobacterial infection


Biography:

Andres Floto is Professor of Respiratory Biology at the University of Cambridge, a Wellcome Trust Senior Investigator, and Research Director of the Cambridge Centre for Lung Infection at Papworth Hospital, Cambridge.

His research is focused on understanding how immune cells interact with bacteria, how intracellular killing and inflammation are regulated and sometimes subverted during infection, how population-level whole genome sequencing can be used to reveal biology of bacterial infection, and how therapeutic enhancement of cell-autonomous immunity may provide novel strategies to treat multi drug resistant pathogens.

Clinically, he specialises in the treatment of patients with Cystic Fibrosis (CF), non-CF bronchiectasis, and infections with Nontuberculous Mycobacteria (NTM). He is co-chair of the British Thoracic Society NTM guidelines committee, the joint US CF Foundation-European CF Society (ECFS) NTM Guidelines Group and the ECFS working group on NTM

Research themes

Host-Pathogen Interactions:
Connections in Africa:
  • K-RITH Centre, Durban, South Africa

Keywords

  • Receptors
  • Signal Transduction
  • Immunology
  • Molecular Biology
  • Macrophages
  • Host-Pathogen Interaction
  • Antimicrobial resistance
  • Innate Immunity
  • Infection
  • Inflammation
  • Immune Evasion
  • Signalling
  • Toll-like receptors

Topics

  • Streptococcus
  • Staphylococcus aureus
  • Tuberculosis