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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

Joel Alves PhD

Joel Alves, PhD

Postdoctoral Researcher

Department of Genetics

Currently studies genetic aspects of host-parasite interactions using as a model the European rabbit and the myxoma virus.


Departments and Institutes

Genetics:

Research Interests

My research interests revolve around population genetics and evolutionary biology in general. I am currently investigating the genetic aspects of host-parasite interactions using as a model the European rabbit and the myxoma virus, an emblematic example of coevolution where less pathogenic strains and resistant hosts have emerged. With this, I am interested in understanding what genomic changes occurred in the rabbit as the result of this evolutionary arms race. This project is a joint collaboration with CIBIO-InBIO - Research Centre in Biodiversity and Genetic Resources (University of Porto, Portugal).

Keywords

  • Host-Pathogen Interaction
  • Genomics
  • Evolution
  • Antiviral resistance

Topics

  • Poxvirus
  • Genomics
  • Aedes aegypti

Key Publications

Crawford J, Alves JM, Palmer WJ, Day JP, Sylla M, Ramasamy R, Surendran SN, Black WC IV, Pain A, Jiggins FM: Population genomics reveals that an anthropophilic population of Aedes aegypti mosquitoes in West Africa recently gave rise to American and Asian populations of this major disease vector. BMC Biology 2017 15:16 (DOI: 10.1186/s12915-017-0351-0)

Alves JM, Carneiro M, Afonso S, Lopes S, Garreau H, Boucher S, Allain D, Queney G, Esteves PJ, Bolet G, Ferrand N: Levels and patterns of genetic diversity and population structure in domestic rabbits. PLoS ONE 2015, 10:e0144687 (DOI: 10.1371/journal.pone.0144687)

Carneiro M, Piorno V, Rubin C-J, Alves JM, Ferrand N, Alves PC, Andersson L: Candidate genes underlying heritable differences in reproductive seasonality between wild and domestic rabbits. Animal Genetics 2015, 46:418-425 (DOI: 10.1111/age.12299)

Carneiro M, Rubin C-J, Di Palma F, Albert FW, Alfoldi J, Barrio AM, Pielberg G, Rafati N, Sayyab S, Turner-Maier J, Younis S, Afonso S, Aken B, Alves JM, et al.: Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication. Science 2014, 345:1074-1079 (DOI: 10.1126/science.1253714)