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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge



  1. Principal Investigators

Principal Investigators

Professor David Aanensen
  • Wellcome Trust Sanger Institute
  • Research and application of genomics for surveillance of high risk lineages of microbial pathogens.
Professor Chris Abell
  • Department of Chemistry
  • Structural biologist focused on fragment based drug discovery and targeting enzymes in Mycobacterium tuberculosis.
Dr James Ajioka
  • Department of Pathology
  • Senior Lecturer in Molecular Parasitology
  • T. gondii genome sequence information to investigate basic properties of the host-parasite interaction.
Professor Stephen Bentley
  • Wellcome Sanger Institute
  • Genomics of bacterial pathogenesis with a particular focus on pneumonia and meningitis
Dr Matt Berriman
  • Wellcome Sanger Institute
  • Matt leads the parasite genomics group who study the parasites that cause malaria and neglected tropical diseases.
Dr Barbara Blacklaws, BSc(Hon), PhD
  • Senior Lecturer in Molecular Virology
01223 337609
Dr Andrew Blagborough
  • Department of Pathology
  • Characterization of malarial transmission and the design of anti-parasitic transmission-blocking interventions
Professor Sir Tom Blundell
  • Department of Biochemistry
  • Structural biology, bioinformatics and drug discovery
Dr. Alex Borodavka
  • Department of Biochemistry, Henry Dale Fellow
  • Interested in the molecular principles of multi-segmented genome packaging and RNA-controlled self-assembly in viruses.
Dr Ian Brierley
  • Translational control
  • Ribosomal frameshifting and readthrough
  • Virus gene expression
  • RNA structure and function
Dr Katherine Brown
  • Department of Physics
  • Development of Therapeutics for Bacterial Infectious Diseases, including Traumatic Injury Infection and Biothreat Agents
Dr Hilary Browne
  • Wellcome Sanger Institute
  • Intestinal microbiota; evolution of intestinal spore-forming bacteria in human gut.
Professor Clare Bryant
  • BBSRC Research Development Fellow
  • Immunopharmacology
01223 766232
Dr Raymond Bujdoso
  • Senior Lecturer in Molecular Immunology
  • Prion diseases
Dr Cinzia Cantacessi
  • Department of Veterinary Medicine
  • Gastrointestinal helminths, host-parasite interactions, high-throughput sequencing technologies.
Professor John Carr
  • Professor of Plant Virology
Dr Mark Carrington
  • Molecular Cell Biology of Trypanosomes
+44 1223 333683
Dr Graham Christie
  • We study bacterial spores (e.g. Bacillus and Clostridium), with a focus on their assembly, structure, and germination.
Professor Pietro Cicuta
  • Department of Physics
  • Salmonella infection of macrophages; bacterial adhesion in airways; P.falciparum (Malaria) egress and invasion in red blood cells; gene expression noise in E.coli; new phenotipic responses to antibiotics; microfluidics/single cell imaging.
Professor P John Clarkson, FREng
  • Department of Engineering
  • Engineering design: including process management, change management, healthcare design and inclusive design.
Dr Andrew Conlan
  • University Senior Lecturer in Epidemiology
+44 (0) 1223 764031
Professor Anne Cooke
  • Professor of Immunobiology
01223 333907
Dr Colin Crump
  • Virus assembly and egress
+44 (0) 1223 763423
Dr Nik Cunniffe
  • Department of Plant Sciences
  • Mathematical modelling of the spread, detection, evolution and control of crop and tree diseases.
Dr Romola Davenport
  • Infectious disease mortality in historical populations; smallpox; tuberculosis ; influenza; puerperal infections
Prof Nick Day
  • Professor of Tropical Medicine, Director of the Mahidol Oxford Tropical Medicine Research Unit, Thailand
Dr Daniela De Angelis
  • Programme leader
  • Statistical methods in epidemic modelling
Janet Deane
  • Molecular mechanisms of host-pathogen interactions during bacterial infection
Ulrich Desselberger, MD FRCPath FRCPG FRCP
  • Molecular biology of rotaviruses
+44 (0)1223 763403
Professor Gordon Dougan, FRS
  • Department of Medicine
  • Vaccinology/pathogenic mechanisms, specialising on the immunology of mucosal vaccines and molecular basis of infection.
Professor David Dunne
  • Epidemiology and Immunology of Schistosomiasis and other Human Parasitic Diseases.
Professor Walderez Dutra
  • Immunoregulatory networks in human parasitic diseases as a tool for understanding pathology and protection.
Dr Brian Ferguson
  • Innate recognition of viruses and vaccine development
Professor Andres Floto
  • Department of Medicine
  • The response of Macrophages and Dendritic cells to bacterial and mycobacterial infection.
Gillian Fraser
  • Senior University Lecturer in Cellular & Molecular Microbiology
  • Head of the Division of Microbiology & Parasitology, Department of Pathology
  • Niccoli Fellow in the Natural Sciences & Director of Studies, Queens' College
Professor Simon Frost
  • Department of Veterinary Medicine
  • Use of mathematical and statistical modelling to understanding the dynamics and evolution of infectious diseases such as HIV, hepatitis C and influenza A.
Professor Chris Gilligan
  • Department of Plant Sciences
  • Epidemiological modelling to predict the spread of plant disease epidemics and to identify and optimise economically and ecologically sustainable strategies for disease management.
Dr Effrossyni Gkrania - Klotsas, MD, MPH, FRCP, PhD
  • A consultant in infectious diseases with an interest in primary and secondary immunodeficiencies and transplantation.
Professor Julia Gog
  • Department of Applied Mathematics and Theoretical Physics (DAMTP)
  • Mathematics of infectious diseases,viral bioinformatics,influenza modelling
Professor Ian Goodfellow
  • Department of Pathology
  • Virus-host interactions, with particular emphasis on noroviruses.
Dr Stephen Graham
  • Molecular mechanisms of membrane trafficking and viral infection
Dr Andrew James Grant
  • Department of Veterinary Medicine
  • Host-pathogen interactions and the molecular basis of virulence.
Dr Harriet Groom , MRSB
  • Honorary Visiting Fellow in the Department of Medicine.
  • I research the molecular interactions between retroviruses and human cells.
Professor Lisa Hall
  • Department of Chemical Engineering & Technology
  • Innovation of cheap diagnostics in developing countries.
Professor Jonathan Luke Heeney
  • Comparative Pathology of Viral Infections
  • Head of the Lab of Viral Zoonotics
Dr Danika Hill
  • Research Fellow, Babraham Institute
  • Lymphocyte Signalling and Development
  • Studying T cell and antibody responses to global health vaccines
Professor Mark A Holmes, MA, VetMB, PhD, FRCVS
  • Professor in Microbial Genomics & Veterinary Science
  • Director of Studies in Clinical Veterinary Medicine (Churchill College)
+44 1223 337636
Professor Christopher Howe
  • We are interested in the molecular biology of the remnant chloroplast (apicoplast) in apicomplexan parasites (e.g. Plasmodium)
David Huggins
  • My research is focused on the development of novel computational methods for developing effective new therapeutics.
Chris Illingworth
  • Study of microbial evolution
Dr Francis Jiggins
  • The evolution and genetics of insects and their pathogens
01223 333175
Dr Robert Kingsley
  • Elucidation of host-Pathogen interactions of enteric bacteria using a genomic and phylogenomic approach.
Professor Andreas Kontoleon
  • Public policy evaluation; Health economics
Dr Mara Lawniczak
  • Group Leader: Vector-parasite interactions
  • We use genomic approaches to better understand mosquito populations and parasite transmission dynamics.
Professor Andrew Lever
  • Department of Medicine
  • Molecular and structural biology of how RNA viruses package their genetic material and how they select their own RNA from the cell so specifically.
Dr Pietro Liò
  • Senior Lecturer in Bioinformatics
Dr. Paula MacGregor
  • Principal Investigator
  • Department of Biochemistry
  • The molecular basis and evolution of host-parasite interactions in African trypanosomes.
Pietro Mastroeni
  • Department of Veterinary Medicine
  • Reader in Infection and Immunity
  • Pathogen behaviour (e.g. location, growth, spread in the body, gene regulation) in vivo at the single cell level in relation to immunity, vaccines and antibiotics.
Dr Nicholas Matheson
  • Viral and cellular regulation of immunometabolism
Professor Ian McConnell
  • Emeritus Professor of Veterinary Science
  • Research Interest Immunology of infection
+44 (0)1223 337654
Richard A. McKay
  • History of Sexually Transmitted Infections and HIV/AIDS, with a particular focus on men who have sex with men (MSM)
Dr Catherine J. Merrick
  • Senior Lecturer, Department of Pathology
  • Basic biology of the human malaria parasite and impact of this biology on virulence. Molecular genetics and cell biology
Dr. Piers D Mitchell
  • Director of the Cambridge Ancient Parasites Laboratory
  • Affiliated Lecturer in Biological Anthropology
  • Hospital Consultant (specialist) in NHS
Dr Yorgo Modis
  • Molecular mechanisms of cell entry, evolution and innate immune recognition of enveloped RNA viruses
01223 267282
Elizabeth Murchison
  • Genetic diversity and evolution in clonally transmissible cancers in dogs and Tasmanian devils
Dr Ankur Mutreja
  • Department of Medicine/CITIID
  • Uses advanced bacterial genomics and metagenomics to understand the evolution and spread of pathogens and mine genomic data to identify robust, risk-informative diagnostic markers
Dr Sergey Nejentsev, MD, PhD
  • Royal Society Research Fellow
Ellen Nisbet
  • Department of Biochemistry
  • Evolution of the Plasmodium apicoplast
Dr Roisin Owens
  • University Lecturer, Chemical Engineering and Biotechnology
  • I develop in vitro models of the gut-brain axis with integrated electronic monitoring.
Rosalind Parkes-Ratanshi
  • My interests are sustainability of HIV services in Africa, fungal infections in Uganda and HIV/STI management
Professor Julian Parkhill, FRS FMedSci
  • Department of Veterinary Medicine
  • The emergence, transmission and evolution of bacterial pathogens.
Nazima Pathan
  • Clinical and research interests in inflammation, sepsis , nutrition and the relationship between gut microbiota and the host
Taufiq Rahman
  • Structure and ligand-guided development of novel small molecule leads against druggable microbial proteins
Professor Lalita Ramakrishnan
  • We are interested in understanding the pathogenesis of tuberculosis and the basis of vastly different susceptibilities to this disease.
Felix Randow
  • Cell autonomous innate immunity, i.e. the ability of individual cells to defend themselves against infection
Professor Julian Rayner
  • Cambridge Institute of Medical Research (CIMR)/Department of Medicine
  • High throughput approaches to understand the biology of malaria parasites and prioritise new drug and vaccine targets
Dr Mansoor Raza
  • Department of Physiology, Development and Neuroscience.
  • Trafficking and processing of bacterial proteins by mammalian cells.
Professor Randy J Read
  • Professor of Protein Crystallography
  • Develop methods for X-ray crystallography and apply to medically-relevant proteins
01223 336500
Dr Olivier Restif
  • Alborada Lecturer in Epidemiology
  • Royal Society University Research Fellow
  • Fellow of Robinson College
Dr Henrik Salje
  • Department of Genetics
  • Applied public health research, especially with regards to the spread of infectious pathogens, and sitting at the interface of mathematical modelling, genetics, population biology, big data, public health and field-based epidemiology.
Professor George Salmond
  • Department of Biochemistry
  • Bacterial Quorum sensing and virulence, regulation and biosynthesis of carbapenem antibiotics and prodigiosin, protein secretion systems, viral abortive infection systems and bacteriophages of plant and animal pathogens.
Dr Crina Samarghitean
  • JBS/Entrepreneurship Centre
  • Develop bioinformatics tools for communicable and non-communicable diseases.
Dr. Manjinder Sandhu
  • Population based, public health and genetic epidemiology studies of chronic infectious and non-infectious diseases.
Dr Sebastian Schornack
  • Gatsby Research Group Leader
  • We study plant processes underlying the accommodation of beneficial and pathogenic microbes.
Professor Alan Short
  • Department of Architecture
  • Focus on ventilation in building design, including hospitals and surgical theatres.
Professor John Sinclair
  • Professor Sinclair’s research interests are in the molecular biology and pathogenesis of human herpes viruses, particularly human cytomegalovirus (HCMV). HCMV is a major cause of disease in transplant patients and patients with AIDS and his research program aims to understand latency and reactivation of this persistent human virus and how the host immune response combats virus disease
Professor Derek Smith
  • Department of Zoology
  • Evolution and population dynamics of antigenically variable pathogens, particularly influenza viruses but also malaria, HIV, and HCV.
Professor Geoffrey Smith
  • Head of Department of Pathology
  • Poxviruses, specifically vaccinia virus, the live vaccine used to eradicate smallpox.
Professor Kenneth Smith
  • Department of Medicine
  • Basic immunological mechanisms, and how defects in regulatory control of the immune system can lead to autoimmunity and alter defence against infection.
Professor David Spring
  • Professor of Chemistry and Chemical Biology
AJ teVelthuis, Dr
  • Department of Pathology
  • How viral RNA polymerases work and contribute to RNA virus pathogenicity.
Dr Laurence S. Tiley
  • Senior Lecturer in Molecular Virology
  • Fellow of Queens' College (Part 1A MIMS supervisor)
  • Biological Safety Officer (Dept. Vet Medicine)
(01223) 339554 (Vet medicine) (01223) 330180 (Queens')
Dr Estee Torok
  • Department of Medicine
  • Current research focuses on translating microbial genomics into clinical practice, and also involved in clinical research in S. aureus, HIV, and tuberculosis.
Dr Flavio Toxvaerd
  • Lecturer in Economics
Dr Caroline Trotter
  • Principal Research Associate, Department of Veterinary Medicine
  • Academic Director Cambridge Africa, Department of Pathology
  • Honorary Epidemiologist at Public Health England
Professor John Trowsdale, PhD FMedSci
  • Professor of Immunology
+44 (0)1223 330248
Dr Hendrik W. van Veen
  • Reader in Molecular Pharmacology
  • -focus on antimicrobial resistance-
Ross Waller
  • Molecular Cell Biology and Evolution of Apicomplexan Parasites
+44 (0)1223 766057
Dr Lucy Weinert
  • Wellcome Trust and Royal Society Henry Dale Fellow
  • Principal Investigator
01223 766247
John Welch
  • Molecular evolution of pathogens
Dr Martin Welch
  • Department of Biochemistry
  • Regulation of microbial virulence and biofilms in Pseudomonas aeruginosa. Quorum sensing, anti-bacterials, stringent response.
Professor Jeremy Wells
  • Department of Veterinary Medicine
  • Host-microbial interactions, mucosal immunology, bacterial infection and immunity, intestinal-health related research.
Shona Wilson
  • The immunology and epidemiology of human schistosomiasis
Professor James Wood
  • Department of Veterinary Medicine
  • Veterinarian, epidemiology with interests in the infection dynamics and control of a number of diseases in Africa and globally.
Gavin Wright
  • I am interested in extracellular receptor-ligand interactions for host-pathogen interactions and reverse vaccinology.
Dr Eiko Yoneki
  • Digital Epidemiology: Modelling of Epidemic Spread using Human Mobility Data from Sensors and Mobile-Phones