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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

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Publication highlights 2013

1.   Whole-genome  sequencing to identify transmission of Mycobacterium abscessus between patients with cystic fibrosis: a retrospective cohort study. Bryant JM, Grogono DM, Greaves D, Foweraker J, Roddick I, Inns T, Reacher M, Haworth CS, Curran MD, Harris SR, Peacock SJ, Parkhill J, Floto RA.Lancet. 2013 May 4;381(9877):1551-60. doi: 10.1016/S0140-6736(13)60632-7. Epub 2013 Mar 29. PubMed

2.  Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC Harrison EM, Paterson GK, Holden MT, Larsen J, Stegger M, Larsen AR, Petersen  A, Skov RL, Christensen JM, Bak Zeuthen A, Heltberg O, Harris SR, Zadoks RN, Parkhill J, Peacock SJ, Holmes MA. . EMBO Mol Med. 2013 Apr;5(4):509-15. doi: 10.1002/emmm.201202413. Epub 2013 Mar 25.

3.  Subpopulations of Staphylococcus aureus clonal complex 121 are associated with distinct clinical entities Kurt K, Rasigade JP, Laurent F, Goering RV, Žemličková H, Machova I, Struelens MJ, Zautner AE, Holtfreter S, Bröker B, Ritchie S, Reaksmey S, Limmathurotsakul D, Peacock SJ, Cuny C, Layer F, Witte W, Nübel U.  PLoS One. 2013;8(3):e58155. doi:10.1371/journal.pone.0058155. Epub 2013 Mar 7.

4.  Epidemiology, microbiology and mortality associated with community-acquired bacteremia in northeast Thailand: a multicenter surveillance study. Kanoksil M, Jatapai A, Peacock SJ, Limmathurotsakul D.  PLoS One. 2013;8(1):e54714. doi: 10.1371/journal.pone.0054714. Epub 2013 Jan 18.

5.  A pilot study of rapid whole-genome sequencing for the  investigation of a Legionella outbreak. Reuter S, Harrison TG, Köser CU, Ellington MJ, Smith GP, Parkhill J, Peacock SJ, Bentley SD, Török ME.  BMJ Open. 2013 Jan 9;3(1). doi:pii: e002175. 10.1136/bmjopen-2012-002175. Print 2013.


6. A Staphylococcus xylosus isolate with a new mecC allotype. Harrison EM, Paterson GK, Holden MT, Morgan FJ, Larsen AR, Petersen A, Leroy S, De Vliegher S, Perreten V, Fox LK, Lam TJ, Sampimon OC, Zadoks RN, Peacock SJ, Parkhill J, Holmes MA.  Antimicrob Agents Chemother. 2013 Mar;57(3):1524-8. doi: 10.1128/AAC.01882-12. Epub 2012 Dec 28.

7. First detection of livestock-associated meticillin-resistant Staphylococcus aureus CC398 in bulk tank milk in the United  Kingdom, January to July 2012. Paterson GK, Larsen J, Harrison EM, Larsen AR, Morgan FJ, Peacock SJ, Parkhill J, Zadoks RN, Holmes MA.  Euro Surveill. 2012 Dec 13;17(50). doi:pii: 20337.

8. Emergence and global spread of epidemic healthcare-associated Clostridium difficile. He M, Miyajima F, Roberts P, Ellison L, Pickard DJ, Martin MJ, Connor TR, Harris SR, Fairley D, Bamford KB, D'Arc S, Brazier J, Brown D, Coia JE, Douce G,  Gerding D, Kim HJ, Koh TH, Kato H, Senoh M, Louie T, Michell S, Butt E, Peacock SJ, Brown NM, Riley T, Songer G, Wilcox M, Pirmohamed M, Kuijper E, Hawkey P, Wren BW, Dougan G, Parkhill J, Lawley TD.  Nat Genet. 2013 Jan;45(1):109-13.
doi: 10.1038/ng.2478. Epub 2012 Dec 9. PubMed PMID:

9. Rapid whole-genome sequencing for investigation of a suspected tuberculosis outbreak. Török ME, Reuter S, Bryant J, Köser CU, Stinchcombe SV, Nazareth B, Ellington MJ, Bentley SD, Smith GP, Parkhill J, Peacock SJ. J Clin Microbiol. 2013 Feb;51(2):611-4. doi: 10.1128/JCM.02279-12. Epub 2012 Nov 21.

10. Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus: a descriptive study. Harris SR, Cartwright EJ, Török ME, Holden MT, Brown NM, Ogilvy-Stuart AL, Ellington MJ, Quail MA, Bentley SD, Parkhill J, Peacock SJ.  Lancet Infect Dis. 2013 Feb;13(2):130-6. doi: 10.1016/S1473-3099(12)70268-2. Epub 2012 Nov 14.