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An Interdisciplinary Research Centre at the University of Cambridge
 

MRSA

  • Strain Collections -  collecting human and animal MRSA strains nationally and internationally to examine genetic differences between strains.
  • Sequencing and bioinformatics - using rapid whole genome sequencing technologies to sequence MRSA strains and evaluating their utility within a routine diagnostic laboratory.
  • Web application - developing an in-hospital web based tool for displaying patient location and MRSA genome sequence variation for MRSA isolates within and between wards.
  • Transmission modelling- modelling patient movements within heathcare facilities and superimposing MRSA sequence data to establish major transmission routes and potential control points
  • Micro-evolutionary analysis - examining MRSA sequence data to determine changes in allele frequency over time and place strains in their phylogenetic and geographical context.
  • Clinical and Public Health - using genomics to improve patient care pathways and inform infection control strategies within the healthcare system