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Dr. Anaid Diaz

Dr.  Anaid  Diaz

Research associate

Department of Veterinary Medicine
Madingley Road
Cambridge CB3 0ES

Biography:

  • 2012-present Postdoc (BBSRC), Dept. of Veterinary Medicine, University of Cambrdige, UK.
  • 2009-2012   Postdoc (NERC), School of Biological Sciences, University of Bristol, UK.
  • 2009   PhD, Dept. of Evolutionary Ecology, University of Glasgow, UK.
  • 2005   MSc, Dept. of Evolutionary Ecology, University of Glasgow, UK.
  • 2003   BSc, Biology, UDLA-P Mexico.

Research themes

Epidemiology and mathematical modelling:

Host-pathogen interaction

Connections in Europe:

Evolution and ecology of Caenorhabditis species

Departments and Institutes

Veterinary Medicine:
Postdoc

Research Interests

My research interests lie in understanding the causes and consequences of life history evolution. These interests include the effects of genetic and environmental variability on population responses.

In my research I use Caenorhabditis species and selection experiments in the laboratory to study life-history evolution. Caenorhabditis species are widely used in research, for instance, to study mechanisms affecting gene expression and their effects on individual’s phenotype.

C. elegans, in particular, is a well established model species in areas such as genetics, developmental biology, reproduction biology or neurology for half a century. This small worm (1mm length) is easy to maintain in the laboratory. It feeds on bacteria and can be grown under controlled conditions over several generations. Not until very recently, it has become obvious of its potential usefulness in epidemiology.

My current project includes setting up a new experimental system to study infection dynamics in microcosms. I am using the nematode C. elegans and bacterial parasites to quantify the dynamics of infection at the individual and population levels, using experiments and mathematical models.

Keywords

  • Evolution
  • Ecology
  • Host-Pathogen Interaction
  • Molecular epidemiology
  • Pathogen Evolution
  • Infection
  • Epidemiology
  • Dynamics

Topics

  • Pseudomonas aeruginosa
  • C. elegans
  • Salmonella

Equipment

  • Mathematical modelling

Key Publications

Diaz S.A. and Restif O. (2014) Spread and transmission of bacterial pathogens in experimental populations of the nematode Caenorhabditis elegansApplied and Environmental Microbiology. doi:10.1128/AEM.01037-14

Diaz S.A. and Viney M. (2014) Genotypic-specific variance in Caenorhabditis elegans lifetime fecundity. Ecology and Evolutiondoi: 10.1002/ece3.1057

Diaz S.A., Brunet V., Lloyd-Jones G., Spinner W., Wharam B. and Viney M. (2014) Diverse and manipulative signalling with ascarosides in the model nematode C. elegans. BMC Evolutionary Biology, 14:46 

Viney M. and Diaz S.A. (2012). Phenotypic plasticity in nematodes: Evolutionary and ecological significance. Worm, 1, pp. 98-106.

Diaz S.A. and Haydon D.T. and Lindström J. (2009) Sperm-limited fecundity and polyandry-induced mortality in female nematodes Caenorhabditis remanei. Biological Journal of the Linnean Society, 99, pp. 362-369.

Diaz S.A., Lindström J. and Haydon D.T. (2008). Basic demography of Caenorhabditis remanei cultured under standard laboratory conditions. Journal of Nematology, 40, pp. 167–178.