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Cambridge Infectious Diseases

The central resource for infectious disease researchers in Cambridge

Studying at Cambridge

 

Dr. Chinyere K. Okoro

Dr. Chinyere K. Okoro

Genetic and evolutionary events that shape the emergence of invasive non-typhoidal Salmonella disease in sub-Saharan Africa.


Research themes

Pathogen Biology and Evolution:
Bacteriology:

Salmonella Genomics

Connections in Africa:

http://www.thrive.cam.ac.uk/

Departments and Institutes

Wellcome Trust Sanger Institute:
Postdoctoral Fellow

Research Interests

Bacterial genomics; phenotype-genotype associations, clinical and public health microbiology

Keywords

  • Genomics
  • Evolution
  • Phylogenetics
  • Molecular Biology
  • Host-Pathogen Interaction
  • Molecular epidemiology
  • Public Health
  • Pathogen Evolution
  • Infection
  • Virulence
  • Pathogenesis
  • Bacteriology
  • Vaccine

Topics

  • Genomics
  • Public Health
  • Salmonella

Collaborators

Key Publications

  • Okoro, C.K. et al.  Intra-continental transmission of human invasive Salmonella Typhimurium pathovariants. Nat. Genet. doi:10.1038/ng.2423 (2012)
  • Okoro, C.K. et al. High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and re-infection in recurrent invasive non-typhoidal Salmonella Typhimurium disease. Clin Infect Dis 54: 955–963 (2012)
  • Seth-Smith H.M.B., Fookes M, Okoro, C.K et al. Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae. J. Bacteriol 194: 1494-504 (2012)
  • Rateb M.E, Houssen, W.E., Harrison WT, Deng H, Okoro, C.K. et al. Diverse metabolic profiles of a Streptomyces strain isolated from a hyper- arid environment. J. Nat. Prod.74, 1965-71 (2011)
  • Rateb, M.E., Houssen W.E., Arnold, M., Abdelrahman, M.H, Deng, H., Harrison, W.T., Okoro, C.K. et al. Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp. J. Nat. Prod. 74:1491-9 (2011)
  • Okoro, C.K et al. Lechevalieria atacamensis sp. nov.,Lechevalieria deserti sp. nov. and Lechevalieria roselyniae sp. nov., isolated from hyperarid soils. Int J Syst Evol Microbiol 60: 296-300 (2010)
  • Okoro, C.K. et al. Diversity of culturable actinomycetes in hyper-arid soils of the Atacama Desert, Chile.  Antonie van Leeuwenhoek 95: 121 -133 (2009)