Research Directory
Professor James Wood
Alborada Professor of Equine and Farm Animal Science
Director, Cambridge Infectious Diseases Consortium
James Wood is interested in taking PhD students.
James Wood is available for consultancy.
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Research Interests
My interests in the Cambridge Infectious Diseases Consortium (CIDC) lie in the dynamics of infections at different scales, from sub-cellular, through to within host and the population level. These dynamics studies rely on collaborations between mathematical modellers (within the vet school (Restif) and in DAMTP (Gog) and basic science researchers and are frequently multi-institutional.
My work, focussed around processes underlying emergence of infectious diseases, is based around mammalian influenza infection, particulalry the dynamics of the generation of viral variants within hosts and during transmission (in collaboration with Kellam at Sanger, Brown at VLA, Murcia at Glasgow and Elton at Animal Health Trust), lyssavirus and henipavirus infections, particularly in African bat reservoir hosts (in collaboration with Cunningham at IoZ, Fooks at VLA and many international collaborators including Webb at Colorado State University) and bovine Tuberculosis persistence and control (in collaboration with VLA and Warwick).
Biography:
I am an infectious disease epidemiologist with interests in the infection dynamics and control of a number of diseases.
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Key Publications
McKinley, T.J., Murcia, P.R., Gog, J.R., Varela, M. & Wood, J.L.N. (2011) A Bayesian approach to analyse genetic variation within RNA viral populations. PLoS Computational Biology 7(3): e1002027. doi:10.1371/journal.pcbi.1002027
Murcia*, P.R., Baillie*, G.J., Daly, J., Elton, D., Jervis, C., Mumford, J.A., Newton, J.R., Parrish, C.R., Hoelzer, K., Dougan, G., Parkhill, J., Lennard, N., Ormond, D., Moule, S., Whitwham, A., McCauley, J.W., McKinley, T.J., Holmes, E.C., Grenfell, B.T.& Wood, J.L.N. (2010) The intra- and inter-host evolutionary dynamics of equine influenza virus. Journal of Virology 84 6943-6954
Wright, E., Hayman, D.T.S., Vaughan, A., Temperton, N.J., Wood, J.L.N., Cunningham, A.A., Suu-Ire, R., Weiss, R.A. Fooks, A.R. (2010) Virus neutralising activity of African fruit bat (Eidolon helvum) sera against 2 emerging lyssaviruses. Virology epub
Hayman, D.T.S., Emmerich, P., Yu, M., Lin-Fa Wang, L.F., Suu‑Ire, R., Fooks, A.R., Cunningham, A.A. and Wood, J.L.N. (2010) Long-term survival of an urban fruit bat seropositive for Ebola and Lagos bat viruses PLoS One 5(8) pii: e11978
Karolemeas, K., McKinley, T.J., Clifton-Hadley, R.S. Goodchild, A.V., Mitchell, A., Johnston, W.T., Conlan, A. J. K., Donnelly, C. A. & Wood, J.L.N. (2010) Predicting prolonged bovine tuberculosis breakdowns in Great Britain as an aid to control. Preventive Veterinary Medicine epub
Park AW, Daly JM, Lewis NS, Smith DJ, Wood JLN, & Grenfell BT, (2009) Quantifying the impact of immune escape on transmission dynamics of influenza. Science 326, 726–8
Hayman DTS, Suu-Ire R, Breed AC, McEachern JA, Wang L, Wood JLN, Cunningham AA, (2008) Evidence of Henipavirus Infection in West African Fruit Bats. PLOS One 3 (7); e2739
Grenfell BT, Pybus OG, Gog JR, Wood JLN, Daly JM, Mumford JA, Holmes EC (2004), “Unifying the epidemiological and evolutionary dynamics of pathogens”, Science 303:327–332
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