Wellcome Sanger Institute

I characterise S. pneumoniae genome collections at the country/GPSC level to infer biologic insights, enrich the project database with genomes from public databases and support external project partners.

I am a molecular and computational microbiologist, with a broad wet and dry lab experience, expertise in genomic laboratory methods and bioinformatics analysis of pathogen genomes, working with viral, fungal and bacterial human pathogens.

What I do:

I am working on making Vibrio cholerae genomic data more useful and usable, particularly using the Pathogenwatch website.

Research Interests:

Vibrio cholerae; Genome variation and genome evolution; Antibiotic resistance; Virulence genes; Mobile genetic elements

The ultimate goal of my current focus is to take advantage of the recently described in vitro co-culture model of Treponema pallidum and link its use to high throughput genomic approaches to provide unique insights into the gene expression profiles of this pathogen.

Research Interests: Genomics, transcriptomics, epidemiology, host-pathogen

Key Projects, Countries, and Partners:

Caroline Zellmer is a microbiologist and PhD student based at the Cambridge Institute of Therapeutic Immunology and Infectious Disease within the Department of Medicine at the University of Cambridge. Her doctoral work will focus on using genomics and applied microbiology to better understand antimicrobial resistance in Klebsiella with the aim of developing novel or repurposing available therapeutics.