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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

Dr Caroline Trotter

Dr Caroline Trotter

Principal Research Associate, Department of Veterinary Medicine

Academic Director Cambridge Africa, Department of Pathology

Honorary Epidemiologist at Public Health England


Biography:

I obtained my first degree in Human Sciences from the University of Oxford, followed by an MSc and PhD in Infectious Disease Epidemiology at the London School of Hygiene and Tropical Medicine. I worked at the Health Protection Agency and then the University of Bristol. In 2013 I moved to Cambridge, joining the Disease Dynamics Unit in the Department of Veterinary Medicine. Since October 2018, I have a joint role as the Academic Director of Cambridge Africa (Department of Pathology). 

Research themes

Infectious Disease Dynamics:

Epidemiology and control of bacterial meningitis and other vaccine-preventable infections

Drugs and Vaccines:

Epidemiology of vaccine preventable infections, mathematical modelling to predict and compare the impact of different immunisation strategies.

Connections in Africa:
  • I have connections in Chad, Ethiopia, Ghana, Mali, Niger, Nigeria and Senegal through the MenAfriCar consortium (www.menafricar.org)
Connections in Europe:

I have connections in Europe through the European Meningococcal Disease Society

Departments and Institutes

Veterinary Medicine:
Principal Research Associate

Research Interests

My research concentrates on understanding the epidemiology of vaccine-preventable diseases and the impact of immunisation. The majority of my work is on meningococcal infection, and I conduct studies in Europe and Africa.  I am also involved in research on group B streptococcus, pneumococcus, rotavirus, norovirus, HPV and rabies.

I use a range of methods including analysis of large databases, systematic reviews, prospective clinical/ field studies, health economics, seroprevalence studies and mathematical modelling. I am most interested in applying these methods to research questions of direct relevance for vaccine policy.

Keywords

  • Health Economics
  • Epidemiology
  • Epidemic control
  • Public Health
  • Infection
  • Immunisation
  • Dynamics

Topics

  • Neisseria meningitidis
  • Meningitis
  • Rabies
  • Streptococcus
  • Streptococcus pneumoniae
  • Norovirus

Equipment

  • Statistical Methods
  • Mathematical modelling

Key Publications

For a full list of my papers click here

WHO Rabies Modelling Consortium (Corresponding authors Trotter CL, Hampson K). The potential impact of improved provision of rabies post-exposure prophylaxis in Gavi-eligible countries: a modelling study. Lancet Infectious Diseases, 2018. DOI:https://doi.org/10.1016/S1473-3099(18)30512-7

Trotter CL, Lingani C, Fernandez K, Cooper LV, Bita A, Tevi-Benissan C, Ronveaux O, Preziosi MP, Stuart JM. The impact of MenAfriVac in nine countries of the African meningitis belt, 2010-2015: an analysis of surveillance data. Lancet Infect Dis 2017, pii: S1473-3099(17)30301-8

Karachaliou A, Conlan AJ, Preziosi MP, Trotter CL. Modeling Long-term Vaccination Strategies With MenAfriVac in the African Meningitis Belt. Clin Infect Dis. 2015;61 Suppl 5:S594-600. doi: 10.1093/cid/civ508

Christensen H, Trotter CL, Hickman M, Edmunds WJ. Re-evaluating the cost-effectiveness of universal ‘MenB’ (Bexsero) vaccination in England: a modelling study. BMJ 2014  349 doi: http://dx.doi.org/10.1136/bmj.g5725 

Daugla DM, Gami JP,  Gamougam K, Naibei N, Mbainadji L, Narbé M,  Toralta J, Kodbesse B, Ngadoua C, Coldiron M, Ferman F, Page A-L,  Djingarey M,  Hugonnet S, Harrison OB, Rebbetts LS, Tekletsion Y, Watkins ER, Caugant DA,  Chandramohan D,  Hassan-King M, Manigart O, Nascimento M, Woukeu A,  Trotter C, Stuart JM, Maiden MCJ, Greenwood B. The impact of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad. Lancet 2014.383:40-7