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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge


Dr Josie Bryant

Dr Josie  Bryant

Henry Wellcome fellow


My research focuses on using whole genome sequencing to understand the evolution of pathogens. I have a particular interest in the within host diversity and evolution of cystic fibrosis pathogens, with a focus on Mycobacterium abscessus and Pseudomonas aeruginosa.

Departments and Institutes



  • Bacteriology
  • Bioinformatics

Key Publications

Bryant JM, Grogono DM, et al: Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium. Science 2016.

Bryant JM, Thibault V, et al:  Phylogenomic exploration of the relationships between strains of Mycobacterium avium subspecies paratuberculosis. BMC Genomics 2016

Bryant JM, Lipman M, Breuer J, Personalizing therapy for multidrug resistant TB: the potential of Rapid Whole Genome Sequencing. Expert review of anti-infective therapy 2016

Bryant JM, Brown AC, et al: Rapid Whole Genome Sequencing of M. tuberculosis directly from clinical samples. Journal of Clinical Microbiology 2015.

Bryant JM, Grogono DM, et al: Whole-genome sequencing to identify transmission of Mycobacterium abscessus between patients with cystic fibrosis: a retrospective cohort study. Lancet 2013.

Bryant JM, Harris SR, et al: Whole genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study. Lancet Respitory Medicine 2013.

Bryant JM, Schurch AC, et al: Inferring patient to patient transmission of Mycobacterium tuberculosis from whole genome sequencing data. BMC Infectious Diseases 2013.


For full list of publications see: