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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge


Dr Sebastian Bruchmann

Dr Sebastian  Bruchmann

Postdoctoral Fellow

I use functional genomics to study AMR and Host-pathogen interactions in Enterobacteriaceae.


I am a postdoctoral fellow in Julian Parkhill’s group with an interest in microbial functional genomics, in particular Klebsiella pneumoniae) and other Enterobacteriaceae species (Salmonella Typhimurium, Enterobacter cloacae).

Departments and Institutes

Veterinary Medicine:

Research Interests

My main research interests are antimicrobial resistance in Enterobacteriaceae and host-pathogen interactions of Klebsiella pneumoniae (especially Klebsiella macrophage interactions). I am using different sequencing-based methods to understand how bacteria cope with certain stresses (gene regulation) and which genes are important during different conditions (gene fitness). I want to know how, when and why genes and their products are used.


  • Genomics
  • Macrophages
  • Host-Pathogen Interaction
  • Antimicrobial resistance
  • Sequencing
  • Gene Expression
  • Gene Regulation


  • Klebsiella