Dr Nisha Singh

What I do: I currently hold a position as a Postdoctoral Fellow at the Wellcome Sanger Institute. My educational background is rooted in Medical Microbiology, and I have developed a robust skill set focused on the isolation, identification, and characterization of microorganisms. One significant aspect of my research involved a comprehensive analysis of the whole genomes of 757 sequenced V. cholerae isolates. This work has significantly contributed to our understanding of the genetic variations and evolutionary patterns within this pathogen, shedding light on various factors such as cholera transmission and antimicrobial resistance.In my current role, I also take on a mentoring role, guiding and supervising PhD students in their research endeavors.

Research Interests: My research interests are primarily focused on the genomics and molecular epidemiology of infectious diseases, with a particular emphasis on cholera. I am passionate about understanding the genetic diversity, evolution, and transmission dynamics of Vibrio cholerae, the causative agent of cholera. By employing advanced genomic sequencing techniques, I aim to decipher the underlying mechanisms that drive the emergence of new cholera strains, antimicrobial resistance patterns, and the global dissemination of this pathogen. Furthermore, I am deeply committed to exploring innovative methods for the rapid and accurate detection and characterization of infectious agents, particularly through the application of molecular biology techniques such as PCR, qPCR and nanopore sequencing. This interest extends to the development of advanced diagnostic tools that can be applied in resource-limited settings, contributing to the early detection and control of infectious disease outbreaks.

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