Host-pathogen interactions

General research description:

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that infects 60-90% of individuals. Following primary infection, HCMV establishes a latent infection under the control of a healthy immune system. Reactivation from viral latency to productive infection causes serious disease in immunocompromised individuals, such as transplant recipients and AIDS patients. Congenital CMV affects 1/100 pregnancies, and is the leading viral cause of birth defects.

Andres Floto is Professor of Respiratory Biology, based at the Victor Philip Dahdaleh Heart and Lung Research Institute, and Co-Director of the Cambridge Centre for AI in Medicine (CCAIM), based at the Department of Applied Maths and Theoretical Physics. He currently co-leads the Cambridge Infectious Diseases Interdisciplinary Research Centre.