Malaria

What I do:

My research interest revolves around understanding the transcriptional regulation of resistance in Plasmodium falciparum. The emergence of resistance requires stringent transcriptional regulation, which in turn is dictated by various key molecular players. Deciphering the role of these molecules can open up more avenue for the development of malaria transmission-blocking intervention strategies.

General research description:

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that infects 60-90% of individuals. Following primary infection, HCMV establishes a latent infection under the control of a healthy immune system. Reactivation from viral latency to productive infection causes serious disease in immunocompromised individuals, such as transplant recipients and AIDS patients. Congenital CMV affects 1/100 pregnancies, and is the leading viral cause of birth defects.