Dr Charlotte Houldcroft

Christ's College crest
Christ's College
  • Assistant professor in virus genomics
Available to supervise doctoral students
Dr Charlotte Houldcroft

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About

Biography

Charlotte is a lecturer in the Department of Genetics, leading the Virus Genomics group.

As an undergraduate she studied Human Sciences at the University of Oxford before a PhD in Molecular Biology at the Wellcome Sanger Institute. Charlotte has also worked at the UCL Institute of Child Health, and the Department of Medicine here in Cambridge.

Charlotte has an interest in how human genetic and immunological variation shape viral diversity, and how viral diversity in turn influences human evolution.

Research

Research interests

  • Host-pathogen interactions
  • Immunology
  • T-Cell

Research interests

I study the evolution and diversity of double-stranded DNA viruses, human pathogens causing diseases as diverse as respiratory infections and fever to chronic nerve pain and cancer. Whole-genome sequencing allows us to track the spread of viruses in space and time; but it also allows us to detect drug resistance, to see the emergence of novel recombinant strains and to study the ancient evolution of successful human pathogens.

Teaching and supervision

Available to supervise doctoral students

Collaborators

  1. Dr Mat Beale

    Dr Mat Beale

    • Postdoctoral Fellow, Parasites and Microbes Programme, Wellcome Sanger Institute
  2. Dr Aminu Jahun

    Dr Aminu Jahun

    • Research Associate, Department of Pathology
  3. Dr Estee Torok

    Dr Estee Torok

    • Senior Program Officer, Malaria / Global Health, Gates Foundation
  4. Dr Jordan Skittrall

    Dr Jordan Skittrall

    • Clinical Lecturer in Virology, Department of Pathology
  5. Dr Josie Bryant

    Dr Josie Bryant

    • Group Leader, Wellcome Sanger Institute
  6. Dr Mark Wills

    Dr Mark Wills

  7. Dr Sarah Jackson

    Dr Sarah Jackson

    • Division of Infectious Disease, Department of Medicine
  8. Dr Stephen Baker

    Dr Stephen Baker

    • Department of Medicine, CITIID.
  9. Dr William Hamilton

    Dr William Hamilton

    • Cambridge University Hospitals NHS Foundation Trust
  10. Dr. Piers Mitchell

    Dr. Piers Mitchell

    • Affiliated researcher, McDonald Institute, Department of Archaeology
  11. Fahad Khokhar

    Fahad Khokhar

    • Research Assistant, Department of Medicine
  12. Professor Ian Goodfellow

    Professor Ian Goodfellow

    • Department of Pathology
  13. Professor Sharon Peacock

    Professor Sharon Peacock

    • Director, COVID-19 genomics UK Consortium (COG-UK) and Professor of Public Health & Microbiology