Biography
My lab investigates the role of the intestinal microbiota in immune responses and pathogen resistance.
Research
We seek mechanistic insights into the influence of commensal microbes on both intestinal infections and inflammation and systemic immune responses. These fundamental insights will give us a better understanding of infectious diseases, autoimmune disorders and even cancer, and will enable the development of new approaches to combat these diseases. Using in vivo models, cellular immunology, transcriptomics and proteomics and working closely with the Wellcome Trust Sanger Institute, we characterise the complex interactions between the commensal microbial community, intestinal epithelium and adaptive immune cells.
Key Projects, Countries, and Partners
Microbial metabolomics with Justin Cross at Memorial Sloan Kettering Cancer Center, New York, USA
