Post-doctoral fellow at the Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus
Hinxton , - CB10 1SA
Websites:
Biography:
I obtained my undergraduate degree in Biochemistry at the University of the Republic in Uruguay (2000-2006). In 2005 I won the "Wellcome Trust Sanger Institute Prize Competition" and was awarded a summer placement at the Institute. During 2007 I undertook an internship at the Schistosomiasis Research Group (University of Cambridge, UK) which turned my interests into Schistosomes. Later that year I started my Ph D studies under the supervision of Dr Matt Berriman (Parasite Genomics group) where I focused on gene expression changes in the early stages host invasion in S.mansoni.
Research themes
- Connections in South America:
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Uruguay. Faculty of Science, Faculty of Chemistry and Faculty of Medicine. Hygiene Institute.
Departments and Institutes
Research Interests
My current research in the Parasite Genomics group is focused in characterising and understanding the mechanisms of gene expression regulation in parasitic worms. Given the good state of its genome assembly and gene annotation, I use S.mansoni as my model organism for this studies. I am mainly interested in functional genomics and gene regulation mechanisms.
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Key Publications
Comparative study of transcriptome profiles of mechanical- and skin-transformed Schistosoma mansoni schistosomula.
Protasio AV, Dunne DW and Berriman M
PLoS neglected tropical diseases 2013;7;3;e2091.PUBMED: 23516644.
A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.
Protasio AV, Tsai IJ, Babbage A, Nichol S, Hunt M, Aslett MA, De Silva N, Velarde GS, Anderson TJ, Clark RC, Davidson C, Dillon GP, Holroyd NE, LoVerde PT, Lloyd C, McQuillan J, Oliveira G, Otto TD, Parker-Manuel SJ, Quail MA, Wilson RA, Zerlotini A, Dunne DW and Berriman M
PLoS neglected tropical diseases 2012;6;1;e1455. PUBMED: 22253936
The genome of the blood fluke Schistosoma mansoni.
Berriman et al.
Nature 2009;460;7253;352-8. PUBMED: 19606141