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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

Anna Victoria Protasio

Anna Victoria Protasio

Post-doctoral fellow at the Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus

Hinxton , - CB10 1SA
Office Phone: 441223495371

Biography:

I obtained my undergraduate degree in Biochemistry at the University of the Republic in Uruguay (2000-2006). In 2005 I won the "Wellcome Trust Sanger Institute Prize Competition" and was awarded a summer placement at the Institute. During 2007 I undertook an internship at the Schistosomiasis Research Group (University of Cambridge, UK) which turned my interests into Schistosomes. Later that year I started my Ph D studies under the supervision of Dr Matt Berriman (Parasite Genomics group) where I focused on gene expression changes in the early stages host invasion in S.mansoni

Research themes

Connections in South America:

Uruguay. Faculty of Science, Faculty of Chemistry and Faculty of Medicine. Hygiene Institute.

Departments and Institutes

Wellcome Sanger Institute:

Research Interests

My current research in the Parasite Genomics group is focused in characterising and understanding the mechanisms of gene expression regulation in parasitic worms. Given the good state of its genome assembly and gene annotation, I use S.mansoni as my model organism for this studies. I am mainly interested in functional genomics and gene regulation mechanisms. 

Keywords

  • Genomics
  • Molecular Biology
  • Parasitology
  • Bioinformatics
  • Gene Expression
  • Gene Regulation

Topics

  • Helminths
  • Schistosomiasis
  • Neglected tropical diseases

Equipment

  • Statistical Methods
  • Cell culture

Key Publications

Comparative study of transcriptome profiles of mechanical- and skin-transformed Schistosoma mansoni schistosomula.
Protasio AV, Dunne DW and Berriman M
PLoS neglected tropical diseases 2013;7;3;e2091.PUBMED: 23516644.

A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.
Protasio AV, Tsai IJ, Babbage A, Nichol S, Hunt M, Aslett MA, De Silva N, Velarde GS, Anderson TJ, Clark RC, Davidson C, Dillon GP, Holroyd NE, LoVerde PT, Lloyd C, McQuillan J, Oliveira G, Otto TD, Parker-Manuel SJ, Quail MA, Wilson RA, Zerlotini A, Dunne DW and Berriman M
PLoS neglected tropical diseases 2012;6;1;e1455. PUBMED: 22253936

The genome of the blood fluke Schistosoma mansoni.
Berriman et al.
Nature 2009;460;7253;352-8. PUBMED: 19606141