Research
Viral Immunology
Sarah studies interactions between viruses and antibodies, with a focus on rotavirus biology and rotavirus vaccination strategies. She is currently funded by a Wellcome Trust Clinical Research Career Development Fellowship.
Sarah also has extensive clinical experience as a small animal veterinary surgeon in private practice, and holds a Diploma from the American College of Veterinary Microbiology.
Publications
Caddy S, Vaysburd M, Papa G, Wing M, O‘Connell K, Stoycheva D, Foss S, Terje Andersen J, Oxenius A, and James LC.Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity. EMBO In press
Caddy S, Vaysburd M, Wing M, Foss S, Terje Andersen J, O‘Connell K, Mayes K, Higginson K, Iturriza-Gómara M, Desselberger U and James LC.Intracellular neutralisation of rotavirus by VP6-specific IgG. PLos Pathogens. 2020;16:e1008732
Caddy S and Goodfellow, I. Complete genome sequence of canine astrovirus with molecular and epidemiological characterisation of UK strains. Veterinary Microbiology. 2015 May 15;177(1-2):206-13
Caddy S, Breiman A, Le Pendu J, Goodfellow I. Genogroup IV and VI canine noroviruses bind to histo-blood groups antigens. Journal of Virology, 2014 15;88(18):10377-91.
Caddy S. Developing a vaccine for covid-19. BMJ 2020;369:m1790 doi: 10.1136/bmj.m1790 and Caddy S. Russian SARS-CoV-2 vaccine. BMJ. 2020;370:10–1 Invited editorials
Ortiz V, Klein L, Channell S, Simpson B, Wright B, Edwards C, Gilbert R, Day R, Caddy S. Evaluating the effect of metronidazole plus amoxicillin‐clavulanate versus amoxicillin‐clavulanate alone in canine haemorrhagic diarrhoea: a randomised controlled trial. JSAP 2018 Jul;59(7):398-403
