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An Interdisciplinary Research Centre at the University of Cambridge


Viral Immunology

Sarah studies interactions between viruses and antibodies, with a focus on rotavirus biology and rotavirus vaccination strategies. She is currently funded by a Wellcome Trust Clinical Research Career Development Fellowship.

Sarah also has extensive clinical experience as a small animal veterinary surgeon in private practice, and holds a Diploma from the American College of Veterinary Microbiology.



Key publications: 

Caddy S, Vaysburd M, Papa G, Wing M, O‘Connell K, Stoycheva D, Foss S, Terje Andersen J, Oxenius A, and James LC.Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity. EMBO In press

Caddy S, Vaysburd M, Wing M, Foss S, Terje Andersen J, O‘Connell K, Mayes K, Higginson K, Iturriza-Gómara M, Desselberger U and James LC.Intracellular neutralisation of rotavirus by VP6-specific IgG. PLos Pathogens2020;16:e1008732

Caddy S and Goodfellow, I. Complete genome sequence of canine astrovirus with molecular and epidemiological characterisation of UK strains. Veterinary Microbiology. 2015 May 15;177(1-2):206-13

Caddy S, Breiman A, Le Pendu J, Goodfellow I. Genogroup IV and VI canine noroviruses bind to histo-blood groups antigens. Journal of Virology, 2014 15;88(18):10377-91. 

Other publications: 

Caddy S. Developing a vaccine for covid-19. BMJ 2020;369:m1790 doi: 10.1136/bmj.m1790 and Caddy S. Russian SARS-CoV-2 vaccine. BMJ. 2020;370:10–1 Invited editorials 

Ortiz V, Klein L, Channell S, Simpson B, Wright B, Edwards C, Gilbert R, Day R, Caddy S. Evaluating the effect of metronidazole plus amoxicillin‐clavulanate versus amoxicillin‐clavulanate alone in canine haemorrhagic diarrhoea: a randomised controlled trial. JSAP 2018 Jul;59(7):398-403

Sarah is a Veterinary Surgeon and Clinical Research Fellow at the Cambridge Institute for Therapeutic Immunology and Infectious Disease (CITIID).
Dr Sarah  Caddy
Available for consultancy


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