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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

AJ teVelthuis Dr

AJ teVelthuis, Dr

Department of Pathology

How viral RNA polymerases work and contribute to RNA virus pathogenicity.


Research Interests

We focus on the replication and transcription of the influenza A virus. This process is driven by the viral RNA polymerase. In addition to copying the viral genome, the RNA polymerase generates aberrant RNA molecules that can induce innate immune responses. To study how the viral RNA polymerase works at a molecular level, we use in vitro activity assays and single-molecule experiments.

Key Projects, Countries, and Partners

Current collaborators:
Prof Wendy Barclay - Imperial College, London, UK
Dr Debby van Riel - Erasmus University, Rotterdam, the Netherlands
Dr Emmie de Wit - NIH, Montana, United States

 

Keywords

  • Enzyme
  • Influenza
  • Gene Expression
  • Viral pathogenicity

Topics

  • Influenza (Flu)
  • RNA virus