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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

Dr Danika Hill

Dr Danika Hill

Research Fellow, Babraham Institute

Lymphocyte Signalling and Development

Studying T cell and antibody responses to global health vaccines


Biography:

Danika Hill's research is focussed on understanding the cellular and molecular mechanisms that underpin robust CD4+ T helper cell responses to vaccination and infection in humans. She is currently investigating immune responses to influenza and malaria using samples from the United Kingdom, Papua New Guinea, Thailand, Mozambique, and Tanzania. Danika has a particular interest in targeting T follicular helper cells to improve vaccine responses, measuring T cell receptor repertoire alterations after vaccination, and developing novel methods to identify antigen-specific CD4+ T cells.

Danika studied Biomedical Science at the University of Adelaide, and completed a PhD at the Walter and Eliza Hall Institute of Medical Research. Since 2015, Danika has been a Postdoc at the Babraham Institute in Cambridge, working with Dr Michelle Linterman.

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCR clonotypes

Authors: Danika L. Hill1†, Wim Pierson1†, Daniel J. Bolland1, Catherine Mkindi2, Edward J. Carr1,3, Jiong Wang4, Sophie Houard5, Steven W. Wingett6, Regine Audran7, Elizabeth F. Wallin8, Said A. Jongo2, Kassim Kamaka2, Martin Zand4, Francois Spertini7, Claudia Daubenberger9,10, Anne E. Corcoran1 and Michelle A. Linterman1*
Affiliations:
1 Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, UK.
2 Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
3 Department of Medicine, University of Cambridge, Cambridge, UK.
4 Division of Nephrology, Department of Medicine and Clinical and Translational Science Institute, University of Rochester Medical Center, Rochester NY, USA.
5 European Vaccine Initiative (EVI), Heidelberg, Germany.
6 Babraham Bioinformatics Facility, Babraham Institute, Cambridge, UK.
7 Division of Immunology and Allergy, CHUV, Lausanne, Switzerland.
8 Renal Department, Lister Hospital, Stevenage, UK
9 Swiss Tropical and Public Health Institute, Basel, Switzerland.
10 University of Basel, Switzerland.

Departments and Institutes

Babraham Institute:
Research Fellow

Keywords

  • Immunology
  • Bioinformatics