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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge
 

Biography

The molecular basis and evolution of host-parasite interactions in African trypanosomes

Research

There are multiple species of African trypanosome that can each infect multiple mammalian hosts. Together they are the causative agents of both human and animal African trypanosomiasis, with bovine trypanosomiasis acting as a major constraint to cattle farming across sub-Saharan Africa.

I am interested in the molecular and cell biology of the interaction between African trypanosomes and their external environment in the mammalian host. Current work in the lab aims to experimentally characterise molecular diversity of the cell surfaces amongst different African trypanosome species and how that affects host-parasite interactions.

Current active projects include;

The molecular basis and evolution of host-parasite interactions in African trypanosomes, Funded by BBSRC David Phillips Fellowship.

Principal Investigator
Department of Biochemistry
The molecular basis and evolution of host-parasite interactions in African trypanosomes.
Dr. Paula  MacGregor
Not available for consultancy

Affiliations

Classifications: 
Person keywords: 
Evolution
Immune Evasion
Molecular Biology
Pathogen Evolution
Infection
Parasitology