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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Vaccines and the discovery of new antimicrobial drugs are one of our most effective means for controlling infectious diseases.

All vaccines rely on one simple principle: give the immune system a head start advantage over the pathogen by teaching it to recognise the pathogen before an actual infection occurs. The immune system then forms a “memory” of the pathogen and can build defences capable of eliminating it and its associated disease during a real infection. They are known to be the safest, most effective way to prevent infectious diseases, and they have enabled the worldwide eradication of many devastating diseases like polio and smallpox. However, vaccines capable of completely protecting against a pathogen as complex as the malaria parasite or TB have never been successfully created, and many logistical and societal challenges to vaccination delivery programmes exist. Here at Cambridge, our researchers are working across disciplines to fast track the scientific discoveries to illuminate fundamental aspects of immunity and responses to infection and examine vaccine delivery and societal challenges and that will enable us to beat these deadly pathogens.

Explore Campus

Work in this area is undertaken in numerous research groups and collaborations across Cambridge, particularly in the Departments of Pharmacology, Pathology, Biochemistry, Veterinary Medicine.

Dr Abiyad  Baig
I am interested in studying the microbial pathogenesis, evolution and diversity using genomics and bioinformatics tools.
Dr Stephen  Baker
Department of Medicine, CITIID.
Molecular microbiologist; enteric infections in developing countries with an emphasis on Norovirus, Shigella spp. and Salmonella Typhi.
Dr Josefin   Bartholdson Scott
Research Associate, Department of Medicine
 Harriet  Bartlett
PhD Candidate
I research livestock sustainability: the relationships between biodiversity loss, GHG emissions, antibiotic use and welfare.
 Carlos    Bastos
Development of metal-based nanominerals for antimicrobial applications.
Dr Andrew  Blagborough
Department of Pathology
Characterization of malarial transmission and the design of anti-parasitic transmission-blocking interventions
Dr Katherine  Brown
Department of Physics
Development of Therapeutics for Bacterial Infectious Diseases, including Traumatic Injury Infection and Biothreat Agents
Professor Clare  Bryant
BBSRC Research Development Fellow
01223 766232
Dr Raymond  Bujdoso
Senior Lecturer in Molecular Immunology
Prion diseases
Dr Sarah  Caddy
Sarah is a Veterinary Surgeon and Clinical Research Fellow at the Cambridge Institute for Therapeutic Immunology and Infectious Disease (CITIID).
Dr. Javier  Castillo-Olivares
Immune Correlates of Protection
Project Coordinator - Human Correlates of Protection of COVID-19 (HICC)
Dr Chrispin  Chaguza
Wellcome Sanger Institute
Molecular epidemiology and evolution of bacterial pathogens particularly Streptococcus pneumoniae
Dr Ruchi   Chauhan
Research Facilitator, Cambridge Academy of Therapeutic Sciences
Facilitates research activities between academic and industry partners via funded exchange programs, educational.
Professor Gordon   Dougan
Department of Medicine
Vaccinology/pathogenic mechanisms, specialising on the immunology of mucosal vaccines and molecular basis of infection.
 Nicholas   Gleadall
Clinical microbiology, development and spread of resistance to antimicrobial and antiviral agents.
Dr Andrew James Grant
Department of Veterinary Medicine
Host-pathogen interactions and the molecular basis of virulence.
Dr. Ian  Groves
Department of Medicine
Targeting latent human cytomegalovirus (HCMV) infection by novel immunotherapeutic strategies in transplant settings
Dr Ewan  Harrison
Wellcome Sanger Institute
Staphylococcus aureus in humans and animals.
 Sarah  James
Part Time Research Associate, Department of Zoology
 Ellis  Kelly
PhD Candidate
Indole signalling in E. coli.
 Rebecca  Kinsley
Postdoctoral Scientist
Vaccine development
 Pietro  Mastroeni
Department of Veterinary Medicine
Reader in Infection and Immunity
Pathogen behaviour (e.g. location, growth, spread in the body, gene regulation) in vivo at the single cell level in relation to immunity, vaccines and antibiotics.
 Ana   Mosterin
I'm a graduate student and administrator in the Pathogen Evolution group. I'm interested in flu and vaccines.
Professor Elizabeth  Murchison
Professor of comparative oncology and genetics
Professor Sharon  Peacock
Director, COVID-19 genomics UK Consortium (COG-UK) and Professor of Public Health & Microbiology
 Arun   Prasad Pandurangan
Investigator Scientist
Department of Structural Studies
Institute MRC Laboratory of Molecular Biology
 Gianmarco   Raddi
Anopheles gambiae hemocyte response to Plasmodium infection
 Taufiq   Rahman
Structure and ligand-guided development of novel small molecule leads against druggable microbial proteins
Professor  Julian   Rayner
Cambridge Institute of Medical Research (CIMR)/Department of Medicine
High throughput approaches to understand the biology of malaria parasites and prioritise new drug and vaccine targets
 Tomas Kappes   Reveco
Bacteriophages host range engineering for biotechnological applications
 Renata  Schaeffer
Assistant Director for Biological Sciences & EU Matters, RO
Research support for School of Biological Sciences and EU funding
Dr. Yoshiro  Shiba
Postdoctoral Scientist
Innovation in drug discovery
Dr Alex  Smith
Department of Veterinary Medicine
Molecular microbiologist using glycoengineering approaches to develop vaccines to prevent bacterial disease in chickens
Dr Hannah   Sore
Antibiotic drug discovery and diagnostic developement
Dr Caroline  Trotter
Principal Research Associate, Department of Veterinary Medicine
Academic Director Cambridge-Africa, Department of Pathology
Honorary Epidemiologist at Public Health England
Dr Sina   Tureli
Research Associate, Department of Zoology
Mathematical modelling of biological systems, dynamical systems
Dr Hendrik W.  van Veen
Reader in Molecular Pharmacology
-focus on antimicrobial resistance-
Dr Tracy  Wang
Animal pathogens, vaccine, antimicrobial resistance and functional genomics
Professor Jeremy  Wells
Department of Veterinary Medicine
Host-microbial interactions, mucosal immunology, bacterial infection and immunity, intestinal-health related research.
Dr Ashraf   Zarkan
Research Associate
Studying the role of indole signalling in Persisters and Biofilm Formation (Aim: Anti-persisters/Anti-biofilm therapy)