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Cambridge Infectious Diseases

An Interdisciplinary Research Centre at the University of Cambridge

Studying at Cambridge

 

Drugs and Vaccines

Vaccines and the discovery of new antimicrobial drugs are one of our most effective means for controlling infectious diseases.

All vaccines rely on one simple principle: give the immune system a head start advantage over the pathogen by teaching it to recognise the pathogen before an actual infection occurs. The immune system then forms a “memory” of the pathogen and can build defences capable of eliminating it and its associated disease during a real infection. They are known to be the safest, most effective way to prevent infectious diseases, and they have enabled the worldwide eradication of many devastating diseases like polio and smallpox. However, vaccines capable of completely protecting against a pathogen as complex as the malaria parasite or TB have never been successfully created, and many logistical and societal challenges to vaccination delivery programmes exist. Here at Cambridge, our researchers are working across disciplines to fast track the scientific discoveries to illuminate fundamental aspects of immunity and responses to infection and examine vaccine delivery and societal challenges and that will enable us to beat these deadly pathogens.

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Work in this area is undertaken in numerous research groups and collaborations across Cambridge, particularly in the Departments of Pharmacology, Pathology, Biochemistry, Veterinary Medicine.

People specializing in this area

Operations Group
Name Phone Email Research Topic
Grant, Andrew ajg60@cam.ac.uk
Steering Committee
Name Phone Email Research Topic
Baker, Stephen
Dougan, Gordon gd312@cam.ac.uk
Grant, Andrew ajg60@cam.ac.uk
Principal Investigators
Name Phone Email Research Topic
Abell, Chris ca26@cam.ac.uk
Blagborough, Andrew amb283@cam.ac.uk
Brown, Katherine kb518@cam.ac.uk

Drugs and Vaccines

Bryant, Clare 01223 766232 ceb27@cam.ac.uk
Bujdoso, Raymond rb202@cam.ac.uk
Dougan, Gordon gd312@cam.ac.uk
Frost, Simon sdf22@cam.ac.uk
Grant, Andrew ajg60@cam.ac.uk
Huggins , David
Mastroeni, Pietro pm274@cam.ac.uk
Murchison, Elizabeth
Okkenhaug, Klaus ko256@cam.ac.uk
Rahman , Taufiq
Rayner, Julian jcr1003@cam.ac.uk
Trotter, Caroline

Epidemiology of vaccine preventable infections, mathematical modelling to predict and compare the impact of different immunisation strategies.

van Veen, Hendrik W. 01223-765295 hwv20@cam.ac.uk
Wells, Jeremy
Postdoctoral Researchers
Name Phone Email Research Topic
Bartholdson Scott, Josefin jb2143@medschl.cam.ac.uk
Burke, David dfb21@cam.ac.uk
Castillo-Olivares, Javier fjc37@cam.ac.uk
Chaguza, Chrispin cc19@sanger.ac.uk
Douse, Christopher cd559@cam.ac.uk
Groves, Ian ijg25@cam.ac.uk
Gupta , Srishti
Harrison, Ewan
Jiang, Xiaowei
Kanvatirth, Panchali pk468@cam.ac.uk
Kinsley, Rebecca rk571@cam.ac.uk
Numata, Shunsuke sn532@cam.ac.uk
Shiba, Yoshiro ys341@cantab.net
Smith, Alex aas93@cam.ac.uk
Sore, Hannah hfs27@cam.ac.uk
Tureli, Sina st757@cam.ac.uk
Wang, Tracy jw401@cam.ac.uk
Zarkan, Ashraf maa77@cam.ac.uk
Graduate Students
Name Phone Email Research Topic
Bartlett, Harriet hb409@cam.ac.uk
Bastos, Carlos
Chen, Bihe
Corney, Matthew mc2114@cam.ac.uk
Gleadall, Nicholas nick.gleadall@googlemail.com
Kelly, Ellis eck32@cam.ac.uk
Mosterin, Ana
Quintero, Alex
Raddi , Gianmarco
Reveco, Tomas Kappes tk510@cam.ac.uk
Associated Professionals
Name Phone Email Research Topic
Chauhan, Ruchi ruchi.chauhan@admin.cam.ac.uk
James, Sarah slj38@cam.ac.uk
Schaeffer, Renata rs530@admin.cam.ac.uk
Whitehorn, James

Research paves way for the development of a vaccine for the contagious cancer which is driving Tasmanian devils to the brink of extinction.

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Targeting the ‘conversations’ that bacteria have with one another could herald a new generation of therapeutics that curb the virulence of infectious microbes.

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Screening method created to expedite the development of new drugs in the fight against tropical diseases such as malaria and African sleeping sickness.

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130225 hivcredit cynthia goldsmith centers for disease control and prevention 2885 x432

Although anti-HIV drugs can significantly prolong life, patients must take the drugs for the rest of their lives. New approaches to therapeutics may hold the answer to finding a cure for HIV.

Cambridge scientists, and their map-making skills, are contributing to an annual worldwide public health endeavour – the race to select a vaccine against seasonal flu.

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Breakthrough could prevent future bird flu epidemics.

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A ‘dipstick’ test that detects Hepatitis B within 30 minutes – and could be used in some of the world’s poorest countries – has been given the green light for use in the European Union.

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A new multidisciplinary research programme aims to develop a single vaccine that will combat four major respiratory pathogens of pigs.

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